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铁道科学与工程学报

JOURNAL OF RAILWAY SCIENCE AND ENGINEERING

Vol. 17    No. 2    April 2007

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Bioactivity of bioresorbable composite based on
bioactive glass and poly-L-lactide
ZHOU Zhi-hua(周智华)1, 2, RUAN Jian-ming(阮建明)1, ZOU Jian-peng(邹俭鹏)1,
ZHOU Zhong-cheng(周忠诚)1, SHEN Xiong-jun(申雄军)1

1.State Key Laboratory of Powder Metallurgy, Central South University,
Changsha 410083, China;
2.College of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China

Abstract: Bioactive and bioresorbable composite was fabricated by a solvent evaporation technique using poly-L-lactide(PLLA) and bioactive glass (average particle size: 6.8 μm). Bioactive glass granules are homogeneously distributed in the composite with microcrack structure. The formation of hydroxyapatite(HA) on the composite in simulated body fluid(SBF) was analyzed by scanning electron microscopy(SEM), energy dispersive spectroscopy(EDS), X-ray diffraction(XRD), and Raman spectra. Rod-like HA crystals deposit on the surface of PLLA/bioactive glass composite after soaking for 3 d. Both rod-like crystals and HA layer form on the surface for 14 d in SBF. The high bioactivity of PLLA/bioactive glass composite indicates the potential of materials for integration with bone.

 

Key words: bioactivity; composite; bioactive glass; poly-L-lactide

ISSN 1672-7029
CN 43-1423/U

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