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铁道科学与工程学报

JOURNAL OF RAILWAY SCIENCE AND ENGINEERING

Vol. 17    No. 3    June 2007

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In vitro biocompatibility of titanium-nickel alloy with titanium oxide film by H2O2 oxidation
HU Tao(胡 涛)1, CHU Cheng-lin(储成林)1, YIN Li-hong(尹立红)2,
PU Yao-pu(浦跃朴)2, DONG Yin-sheng(董寅生)1, GUO Chao(郭 超)1,
SHENG Xiao-bo(盛晓波)1, CHUNG Jonathan-CY(钟志源)3,
CHU Paul-K(朱

1. School of Materials Science and Engineering, Southeast University,
Nanjing 211189, China;
2. School of Public Health, Southeast University, Nanjing 210096, China;
3. Department of Physics and Materials Science, City University of Hong Kong,
Hong Kong, China

Abstract:Titanium oxide film with a graded interface to NiTi matrix was synthesized in situ on NiTi shape memory alloy(SMA) by oxidation in H2O2 solution. In vitro studies including contact angle measurement, hemolysis, MTT cytotoxicity and cell morphology tests were employed to investigate the biocompatibility of the H2O2-oxidized NiTi SMAs with this titanium oxide film. The results reveal that wettability, blood compatibility and fibroblasts compatibility of NiTi SMA are improved by the coating of titanium oxide film through H2O2 oxidation treatment.

 

Key words: NiTi shape memory alloy; titanium oxide film; biocompatibility; wettability; cytocompatibility

ISSN 1672-7029
CN 43-1423/U

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