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铁道科学与工程学报

JOURNAL OF RAILWAY SCIENCE AND ENGINEERING

Vol. 14    No. 1    February 2004

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Preparation and characterization of nano hydroxyapatite sol
WANG You-fa(王友法), YAN Yu-hua(闫玉华), REN Wei(任 卫),
CAO Xian-ying(曹献英), LI Shi-pu(李世普)

Biomaterials and Engineering Research Center, Wuhan University of Technology, Wuhan 430070, China

Abstract:Nano hydroxyapatite has special biological effects when it interacts with cells. The method of preparation of nano hydroxyapatite crystals in water and the stability of hydroxyapatite sol are reported. Nanometer sized hydroxyapatite crystals were synthesized by precipitation with monocalcium phosphate and calcium hydroxide. The size of the crystals is 30 50 nm as determined by laser light scattering and transmission electron microscopy (TEM). The shape of the crystals particles is either sphere or rod-shaped. Beijing Synchrotron Radiation Facility (BSRF) micro-probe X-ray fluorescence analysis and TEM analysis reveal that hydroxyapatite crystals can pass human liver cancer cell membrane in the form of particles.

 

Key words: hydroxyapatite; nano crystals; disperse characteristics; stability

ISSN 1672-7029
CN 43-1423/U

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